Sero-Prevalence of Hepatitis B and Associated Risk Factors among HIV/ ADIS Patients Attending Debark Hospital, Northwest Ethiopia

Abstract

Hepatitis B is the most critical and prevalent infectious virus leading to human liver
inflammation. HIV infection and intravenous drug use are directly related to the prevalence of
Hepatitis B in different nations, regions, and populations. The general objective of the present
study is to determine the prevalence and associated risk factors of Hepatitis B Virus infection
among HIV/ADIS patients attending Debark Hospital, Northwest Ethiopia. A hospital-based
cross-sectional study was conducted on 113 volunteer HIV/AIDs patients attending at Debark
Hospital from February to June, 2018. The test for Hepatitis B surface antigen (HBsAg) was
done using a rapid diagnostic test kit, according to the manufacturer's instructions (One Step
HBsAg test, Ameritech-china, Ltd. Seattle, Washington, USA). An interviewer-administered
pretested questionnaire was used to collect data on demographic information and other factors
associated with HBV infection. Analysis of data was conducted using the SPSS version 20
statistical package. The results were summarized using descriptive statistics and univariate and
multivariate logistic regression. The overall prevalence of HBV was 6.2%. The prevalence in
females was 6.9%, with males accounting for 4.9%. Rural residence (COR = 6.667, 95CI, 1,06-
41.77, P-value=0.025), having multiple sexual partners (COR = 5.365, 95CI = 1.077-26.77, Pvalue=0.040), having surgical history (COR=8.76,95 CI = 1.77-43.34, P-value=0.001), and
having dental procedure (COR = 4.125, 95CI =1.076-22.27, P-value=0.01) were associated
with a statistically significant increased risk of HBV infections. The result uses to develop
appropriate preventive services, allocate resources decided on priorities and target populations
with HIV/AIDS.