Sero-Prevalence of Hepatitis B and Associated Risk Factors among HIV/ ADIS Patients Attending Debark Hospital, Northwest Ethiopia

Abstract

Hepatitis B is the most critical and prevalent infectious virus leading to human liver inflammation. HIV infection and intravenous drug use are directly related to the prevalence of Hepatitis B in different nations, regions, and populations. The general objective of the present study is to determine the prevalence and associated risk factors of Hepatitis B Virus infection among HIV/ADIS patients attending Debark Hospital, Northwest Ethiopia. A hospital-based cross-sectional study was conducted on 113 volunteer HIV/AIDs patients attending Debark Hospital from February to June 2018. The test for Hepatitis B surface antigen (HBsAg) was done using a rapid diagnostic test kit, according to the manufacturer's instructions (One Step HBsAg test, Ameritech-china, Ltd. Seattle, Washington, USA). An interviewer-administered pretested questionnaire was used to collect data on demographic information and other factors associated with HBV infection. Analysis of data was conducted using the SPSS version 20 statistical package. The results were summarized using descriptive statistics and univariate and multivariate logistic regression. The overall prevalence of HBV was 6.2%. The prevalence in females was 6.9%, with males accounting for 4.9%. Rural residence (COR = 6.667, 95CI, 1,06-41.77, P-value=0.025), having multiple sexual partners (COR = 5.365, 95CI = 1.077-26.77,  Pvalue=0.040), having surgical history (COR=8.76,95 CI = 1.77-43.34, P-value=0.001), and having dental procedure (COR = 4.125, 95CI =1.076-22.27, P-value=0.01) were associated with a statistically significant increased risk of HBV infections. The result is used to develop appropriate preventive services, allocate resources decided on priorities, and target populations with HIV/AIDS.